Association of sugary drink consumption with all-cause and cause-specific mortality: the Japan Public Health Center-based Prospective Study.
Hsi-Lan Huang, Sarah Krull Abe, Norie Sawada, Ribeka Takachi, Junko Ishihara, Motoki Iwasaki, Taiki Yamaji, Hiroyasu Iso, Tetsuya Mizoue, Mitsuhiko Noda, Masahiro Hashizume, Manami Inoue, Shoichiro Tsugane
Preventive medicine. 2021 07;148;106561. pii: S0091-7435(21)00145-6.
Few epidemiologic studies have assessed the associations of sugary drink consumption with mortality outcomes among Asian populations.
This study included 70,486 participants in the Japan Public Health Center-based Prospective Study at the age of 45-74 years in 1995-1999. A validated food frequency questionnaire was used to assess the consumption of sugary drinks. We estimated the risk of total and cause-specific mortality associated with sugary drink consumption using Cox proportional hazards regression model.
Mean follow-up was 17.1 years, during which 11,811 deaths were documented. Sugary drink consumption was associated with higher total mortality, with multivariate HR of 1.06 (95% CI 1.00-1.13) for quintile 3, 1.07 (95% CI 1.01-1.13) for quintile 4, and 1.15 (95% CI 1.09-1.22) for quintile 5, compared with quintile 1 (P < 0.001 for trend). Additionally, positive associations with cause-specific mortality were observed, including death from circulatory system diseases (quintile 5 vs quintile 1; HR, 1.23; 95% CI 1.09-1.38) and heart disease (quintile 5 vs quintile 1; HR, 1.35; 95% CI 1.14-1.60).
In this large Japanese prospective study, sugary drink consumption was associated with all-cause and cause-specific mortality.
Association of Sugary Beverage Consumption With Mortality Risk in US Adults
A Secondary Analysis of Data From the REGARDS Study
Lindsay J. Collin, MPH; Suzanne Judd, PhD; Monika Safford, MD, PhD; et al
Viola Vaccarino, MD, PhD; Jean A. Welsh, RN, MPH, PhD
JAMA Netw Open. 2019;2(5):e193121. doi:10.1001/jamanetworkopen.2019.3121